Increased mortality in elderly patients w/ dementia-related psychosis. Cerebrovascular adverse events, including stroke, in elderly patients w/ dementia-related psychosis. Discontinue treatment if neuroleptic malignant syndrome or tardive dyskinesia occurs. Avoid in combination w/ drugs that prolong QTc, patients w/ congenital QT syndrome or history of cardiac arrhythmias. Monitor for metabolic changes (hyperglycemia, DM & wt gain). Hyperprolactinemia. Monitor orthostatic vital signs in patients vulnerable to hypotension. Reports of somnolence, postural hypotension, motor & sensory instability. Leukopenia, neutropenia & agranulocytosis. Use cautiously in patients w/ history of seizures or w/ conditions that lower seizure threshold; in patients at risk for aspiration pneumonia. Patients w/ Parkinson's disease or dementia w/ Lewy bodies can experience increased sensitivity to Invega Sustenna. Priapism. Conditions that contribute to core body temp elevation or dehydration. Avoid inj into a blood vessel. Moderate to severe renal impairment (CrCl <50 mL/min). Use caution when performing activities requiring mental alertness. Pregnancy & lactation. Childn <18 yr. Elderly.
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